Detecting Small Changes in the Shapes of Proteins

Biochemical reactions can lead to changes in the shapes or conformations of proteins. The conformation of proteins is connected with their functions and protein functions are key to understanding cellular functions. Therefore an understanding of how protein shapes change reveals much about the dynamics of cellular function. Surface Plasmon Resonance (SPR) is a technological approach used to detect small conformational changes.

Biosensing Instrument Incorporated provides Surface Plasmon Resonance (SPR) instruments for research and analysis. Their website is linked to here.